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Role of (p)ppGpp in biofilm formation by Enterococcus faecalis.


ABSTRACT: Enterococcus faecalis strain OG1RF and its (p)ppGpp-deficient ?relA, ?relQ, and ?relA ?relQ mutants were grown in biofilms and evaluated for growth profiles, biofilm morphology, cell viability, and proteolytic activity. E. faecalis lacking (p)ppGpp had a diminished capacity to sustain biofilm formation over an extended period of time and expressed abundant proteolytic activity.

SUBMITTER: Chavez de Paz LE 

PROVIDER: S-EPMC3294496 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature

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Role of (p)ppGpp in biofilm formation by Enterococcus faecalis.

Chávez de Paz Luis E LE   Chávez de Paz Luis E LE   Lemos José A JA   Wickström Claes C   Sedgley Christine M CM  

Applied and environmental microbiology 20111216 5


Enterococcus faecalis strain OG1RF and its (p)ppGpp-deficient ΔrelA, ΔrelQ, and ΔrelA ΔrelQ mutants were grown in biofilms and evaluated for growth profiles, biofilm morphology, cell viability, and proteolytic activity. E. faecalis lacking (p)ppGpp had a diminished capacity to sustain biofilm formation over an extended period of time and expressed abundant proteolytic activity. ...[more]

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