Discordance among commercially available diagnostics for latent tuberculosis infection.

ABSTRACT:

Rationale

There is uncertainty regarding how to interpret discordance between tests for latent tuberculosis infection.

Objectives

The objective of this study was to assess discordance between commercially available tests for latent tuberculosis in a low-prevalence population, including the impact of nontuberculous mycobacteria.

Methods

This was a cross-sectional comparison study among 2,017 military recruits at Fort Jackson, South Carolina, from April to June 2009. Several tests were performed simultaneously with a risk factor questionnaire, including (1) QuantiFERON-TB Gold In-Tube test, (2) T-SPOT.TB test, (3) tuberculin skin test, and (4) Battey skin test using purified protein derivative from the Battey bacillus.

Measurements and main results

In this low-pr

SUBMITTER: Mancuso JD 

PROVIDER: S-EPMC3297098 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature