The bacterial Sec-translocase: structure and mechanism.

ABSTRACT: Most bacterial secretory proteins pass across the cytoplasmic membrane via the translocase, which consists of a protein-conducting channel SecYEG and an ATP-dependent motor protein SecA. The ancillary SecDF membrane protein complex promotes the final stages of translocation. Recent years have seen a major advance in our understanding of the structural and biochemical basis of protein translocation, and this has led to a detailed model of the translocation mechanism.

SUBMITTER: Lycklama A Nijeholt JA 

PROVIDER: S-EPMC3297432 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature