Target product profiles for protecting against outdoor malaria transmission.

ABSTRACT:

Background

Long-lasting insecticidal nets (LLINs) and indoor residual sprays (IRS) have decimated malaria transmission by killing indoor-feeding mosquitoes. However, complete elimination of malaria transmission with these proven methods is confounded by vectors that evade pesticide contact by feeding outdoors.

Methods

For any assumed level of indoor coverage and personal protective efficacy with insecticidal products, process-explicit malaria transmission models suggest that insecticides that repel mosquitoes will achieve less impact upon transmission than those that kill them outright. Here such models are extended to explore how outdoor use of products containing either contact toxins or spatial repellents might augment or attenuate impact of high indoor coverage of LLINs

SUBMITTER: Killeen GF 

PROVIDER: S-EPMC3298720 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature