Ontology highlight
ABSTRACT:
SUBMITTER: Chen YC
PROVIDER: S-EPMC3302151 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Cell metabolism 20120301 3
The complexes of the electron transport chain associate into large macromolecular assemblies, which are believed to facilitate efficient electron flow. We have identified a conserved mitochondrial protein, named respiratory supercomplex factor 1 (Rcf1-Yml030w), that is required for the normal assembly of respiratory supercomplexes. We demonstrate that Rcf1 stably and independently associates with both Complex III and Complex IV of the electron transport chain. Deletion of the RCF1 gene caused im ...[more]