Frequent ice cream consumption is associated with reduced striatal response to receipt of an ice cream-based milkshake.

ABSTRACT:

Background

Weight gain leads to reduced reward-region responsivity to energy-dense food receipt, and consumption of an energy-dense diet compared with an isocaloric, low-energy-density diet leads to reduced dopamine receptors. Furthermore, phasic dopamine signaling to palatable food receipt decreases after repeated intake of that food, which collectively suggests that frequent intake of an energy-dense food may reduce striatal response to receipt of that food.

Objective

We tested the hypothesis that frequent ice cream consumption would be associated with reduced activation in reward-related brain regions (eg, striatum) in response to receipt of an ice cream-based milkshake and examined the influence of adipose tissue and the specificity of this relation.

Design

Health

SUBMITTER: Burger KS 

PROVIDER: S-EPMC3302359 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature