Infant regulation of intake: the effect of free glutamate content in infant formulas.

ABSTRACT:

Background

We recently discovered that infants randomly assigned to a formula high in free amino acids (extensive protein hydrolysate formula; ePHF) during infancy consumed less formula to satiation and gained less weight than did infants fed an isocaloric formula low in free amino acids (cow milk formula; CMF).

Objective

Because ePHF and CMF differ markedly in concentrations of free glutamate, we tested the hypothesis that the higher glutamate concentrations in ePHF promote satiation and satiety.

Design

In this counterbalanced, within-subject study, infants <4 mo of age (n = 30) visited our laboratory for 3 sets of 2 consecutive infant-led formula meals over 3 test days. Infants were fed 1 of 3 isocaloric formulas during each first meal: CMF, ePHF, or CMF with added

SUBMITTER: Ventura AK 

PROVIDER: S-EPMC3302362 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature