Magnetic resonance microscopy of human and porcine neurons and cellular processes.

ABSTRACT: With its unparalleled ability to safely generate high-contrast images of soft tissues, magnetic resonance imaging (MRI) has remained at the forefront of diagnostic clinical medicine. Unfortunately due to resolution limitations, clinical scans are most useful for detecting macroscopic structural changes associated with a small number of pathologies. Moreover, due to a longstanding inability to directly observe magnetic resonance (MR) signal behavior at the cellular level, such information is poorly characterized and generally must be inferred. With the advent of the MR microscope in 1986 came the ability to measure MR signal properties of theretofore unobservable tissue structures. Recently, further improvements in hardware technology have made possible the ability to visualize mammalian ce

SUBMITTER: Flint JJ 

PROVIDER: S-EPMC3304009 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature