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A highly efficient green synthesis of 1, 8-dioxo-octahydroxanthenes.

ABSTRACT: SmCl3 (20 mol%) has been used as an efficient catalyst for reaction between aromatic aldehydes and 5,5-dimethyl-1,3-cyclohexanedione at 120°C to give 1,8-dioxo-octahydroxanthene derivatives in high yield. The same reaction in water, at room temperature gave only the open chain analogue of 1,8-dioxo-octahydroxanthene. Use of eco-friendly green Lewis acid, readily available catalyst and easy isolation of the product makes this a convenient method for the synthesis of either of the products.

SUBMITTER: Ilangovan A

PROVIDER: S-EPMC3305897 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature

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A highly efficient green synthesis of 1, 8-dioxo-octahydroxanthenes.

Ilangovan Andivelu A Malayappasamy Subramani S Muralidharan Samraj S Maruthamuthu Sundaram S

Chemistry Central journal 20111208

SmCl3 (20 mol%) has been used as an efficient catalyst for reaction between aromatic aldehydes and 5,5-dimethyl-1,3-cyclohexanedione at 120°C to give 1,8-dioxo-octahydroxanthene derivatives in high yield. The same reaction in water, at room temperature gave only the open chain analogue of 1,8-dioxo-octahydroxanthene. Use of eco-friendly green Lewis acid, readily available catalyst and easy isolation of the product makes this a convenient method for the synthesis of either of the products. ...[more]

PMID: 22152051

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