Genome-wide association analysis of Sasang constitution in the Korean population.

ABSTRACT:

Objectives

Sasang constitutional medicine is a traditional Korean medicine in which an individual is classified into one of four types of constitution: Taeum (TE), Soeum (SE) Soyang (SY), and Taeyang (TY). These constitution types are determined with biologic and physiologic characteristics, so it has been assumed that genetic factors are associated with each constitution type. Identifying the genetic elements underlying each constitution is necessary for the elucidation of the molecular mechanism of Sasang constitutional medicine.

Design

A total of 341,998 genetic loci across the whole genome were genotyped for 1222 subjects of defined constitution type. The genetic loci associated with each constitution type were identified and the functional connectivity of genes within t

SUBMITTER: Kim BY 

PROVIDER: S-EPMC3306582 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature