A retrospective cross-sectional study of risk factors and clinical spectrum of children admitted to hospital with pandemic H1N1 influenza as compared to influenza A.

ABSTRACT:

Objective

To compare risk factors for severe disease as measured by admission to hospital and intensive care unit (ICU) and other clinical outcomes in children with pandemic H1N1 (pH1N1) versus those with seasonal influenza.

Design

Retrospective analysis of children admitted to hospital with pH1N1 versus seasonal influenza A.

Setting

Canadian tertiary referral children's hospital.

Participants

All laboratory-identified cases of pH1N1 in children younger than 18 years admitted to hospital in 2009 (n=176) and all seasonal influenza A cases admitted to hospital from influenza seasons 2004-2005 to 2008-2009 (n=200). Children with onset of symptoms more than 3 days after admission were excluded.

Primary and secondary outcome measures

Primary outcomes include

SUBMITTER: Morris SK 

PROVIDER: S-EPMC3307038 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature