Distribution and associations of [-2]proenzyme-prostate specific antigen in community dwelling black and white men.

ABSTRACT:

Purpose

We provide cross-sectional normative data on [-2]proenzyme-prostate specific antigen from the Olmsted County Study of Urinary Symptoms and Health Status among Men, and the Flint Men's Health Study. We also describe associations with clinical urological measures and the risk of prostate cancer diagnosis.

Materials and methods

Measurements of [-2]proenzyme-prostate specific antigen were obtained from 420 white men from Olmsted County, Minnesota, and 328 black men from Genesee County, Michigan. Cross-sectional associations between [-2]proenzyme-prostate specific antigen and prostate enlargement/elevated prostate specific antigen were assessed. Cox proportional hazard models were used to assess associations between [-2]proenzyme-prostate specific antigen and the incident

SUBMITTER: Rhodes T 

PROVIDER: S-EPMC3307097 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature