Ontology highlight
ABSTRACT:
SUBMITTER: Royo JL
PROVIDER: S-EPMC3308983 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
PloS one 20120320 3
Meis1, a conserved transcription factor of the TALE-homeodomain class, is expressed in a wide variety of tissues during development. Its complex expression pattern is likely to be controlled by an equally complex regulatory landscape. Here we have scanned the Meis1 locus for regulatory elements and found 13 non-coding regions, highly conserved between humans and teleost fishes, that have enhancer activity in stable transgenic zebrafish lines. All these regions are syntenic in most vertebrates. T ...[more]