Density gradient multilayer polymerization for creating complex tissue.

ABSTRACT: An adaptable density gradient multilayer polymerization (DGMP) method facilitates simple fabrication of complex multicompartment scaffolds with structurally continuous interfaces. Solvent density liquid-liquid phase segregation compartmentalizes varied mechanical and chemical cues independently. Bulk photopolymerization produces stratified three-dimensional and two-dimensional matrices. Cells attach to patterned adhesion peptides on biomimetic 2D substrates.

SUBMITTER: Karpiak JV 

PROVIDER: S-EPMC3309044 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature