Internal growth of nonsolid lung nodules: radiologic-pathologic correlation.

ABSTRACT:

Purpose

To determine whether computed tomographic (CT) attenuation values correlate with the histologic measurements of a lung cancer manifesting as a nonsolid nodule and to quantify the extent to which the tumor replaces the airspace within the nodule.

Materials and methods

Informed consent was obtained to analyze images from CT and pathologic examination under an institutional review board-approved protocol. Fifteen patients who had undergone resection of nonsolid lung cancer were evaluated. On the basis of the CT attenuation values of nonsolid nodules, nonneoplastic lung, soft tissue, and air, the overall proportion of soft tissue in the nodule and nonneoplastic lung and the difference between these two measures were calculated. The analogous measures were obtained from a

SUBMITTER: Zhang L 

PROVIDER: S-EPMC3309799 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature