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Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic.


ABSTRACT:

Background

Yaws is a bacterial skin and bone infectious disease caused by Treponema pallidum pertenue. It is endemic, particularly among pygmies in Central African Republic. To assess the clinical cure rate after treatment with benzathinepenicillin in this population, we conducted a cohort survey of 243 patients in the Lobaye region.

Findings and conclusion

The rate of healing of lesions after 5 months was 95.9%. This relatively satisfactory level of therapeutic response implies that yaws could be controlled in the Central African Republic. Thus, reinforcement of the management of new cases and of contacts is suggested.

SUBMITTER: Manirakiza A 

PROVIDER: S-EPMC3309964 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature

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Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic.

Manirakiza Alexandre A   Boas Susana Vilas SV   Beyam Narcisse N   Zadanga Germain G   Konamna François Xavier FX   Njuimo Siméon P SP   Laganier Rémi R  

BMC research notes 20111215


<h4>Background</h4>Yaws is a bacterial skin and bone infectious disease caused by Treponema pallidum pertenue. It is endemic, particularly among pygmies in Central African Republic. To assess the clinical cure rate after treatment with benzathinepenicillin in this population, we conducted a cohort survey of 243 patients in the Lobaye region.<h4>Findings and conclusion</h4>The rate of healing of lesions after 5 months was 95.9%. This relatively satisfactory level of therapeutic response implies t  ...[more]

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