Molecular evolution of respiratory syncytial virus fusion gene, Canada, 2006-2010.

ABSTRACT: To assess molecular evolution of the respiratory syncytial virus (RSV) fusion gene, we analyzed RSV-positive specimens from 123 children in Canada who did or did not receive RSV immunoprophylaxis (palivizumab) during 2006-2010. Resistance-conferring mutations within the palivizumab binding site occurred in 8.7% of palivizumab recipients and none of the nonrecipients.

SUBMITTER: Papenburg J 

PROVIDER: S-EPMC3310097 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature