Considerations for oral cholera vaccine use during outbreak after earthquake in Haiti, 2010-2011.

ABSTRACT: Oral cholera vaccines (OCVs) have been recommended in cholera-endemic settings and preemptively during outbreaks and complex emergencies. However, experience and guidelines for reactive use after an outbreak has started are limited. In 2010, after over a century without epidemic cholera, an outbreak was reported in Haiti after an earthquake. As intensive nonvaccine cholera control measures were initiated, the feasibility of OCV use was considered. We reviewed OCV characteristics and recommendations for their use and assessed global vaccine availability and capacity to implement a vaccination campaign. Real-time modeling was conducted to estimate vaccine impact. Ultimately, cholera vaccination was not implemented because of limited vaccine availability, complex logistical and operational ch

SUBMITTER: Date KA 

PROVIDER: S-EPMC3310586 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature