Reconstruction and analysis of a genome-scale metabolic model for Scheffersomyces stipitis.

ABSTRACT:

Background

Fermentation of xylose, the major component in hemicellulose, is essential for economic conversion of lignocellulosic biomass to fuels and chemicals. The yeast Scheffersomyces stipitis (formerly known as Pichia stipitis) has the highest known native capacity for xylose fermentation and possesses several genes for lignocellulose bioconversion in its genome. Understanding the metabolism of this yeast at a global scale, by reconstructing the genome scale metabolic model, is essential for manipulating its metabolic capabilities and for successful transfer of its capabilities to other industrial microbes.

Results

We present a genome-scale metabolic model for Scheffersomyces stipitis, a native xylose utilizing yeast. The model was reconstructed based on genome sequence

SUBMITTER: Balagurunathan B 

PROVIDER: S-EPMC3310799 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature