Performance evaluation of the Pima™ point-of-care CD4 analyser using capillary blood sampling in field tests in South Africa.

ABSTRACT:

Background

Point-of-care CD4 testing can provide immediate CD4 reporting at HIV-testing sites. This study evaluated performance of capillary blood sampling using the point-of-care Pima™ CD4 device in representative primary health care clinics doing HIV testing.

Methods

Prior to testing, prescribed capillary-sampling and instrument training was undertaken by suppliers across all sites. Matching venous EDTA samples were drawn throughout for comparison to laboratory predicate methodology (PLG/CD4). In Phase I, Pima™ cartridges were pipette-filled with EDTA venous blood in the laboratory (N = 100). In Phase II (N = 77), Pima™ CD4 with capillary sampling was performed by a single operator in a hospital-based antenatal clinic. During subsequent field testing, Pima™ CD4 with capill

SUBMITTER: Glencross DK 

PROVIDER: S-EPMC3310849 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature