An endogenous bile acid and dietary sucrose from skin secretions of alkaloid-sequestering poison frogs.

ABSTRACT: The skins of Madagascar poison frogs (Mantella) and certain Neotropical poison frogs (Epipedobates, Dendrobates) secrete the new bile acid tauromantellic acid (1), which was found in both wild-caught and captive-born frogs. This is the first molecule of endogenous origin detected in skin secretions from these taxa. Sucrose was also detected in secretions from wild-caught Mantella but not in captive-born frogs, suggesting a dietary origin.

SUBMITTER: Clark VC 

PROVIDER: S-EPMC3311751 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature