Rhodium(I)/diene-catalyzed addition reactions of arylborons with ketones.

ABSTRACT: Rh(I)/diene-catalyzed addition reactions of arylboroxines/arylboronic acids with unactivated ketones to form tertiary alcohols in good to excellent yields are described. By using C(2)-symmetric (3aR,6aR)-3,6-diaryl-1,3a,4,6a-tetrahydropentalenes as ligands, the asymmetric version of such an addition reaction, with up to 68% ee, was also realized.

SUBMITTER: Liao YX 

PROVIDER: S-EPMC3312017 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature