Low prevalence of chronic beryllium disease among workers at a nuclear weapons research and development facility.

ABSTRACT:

Objective

To study the prevalence of beryllium sensitization (BeS) and chronic beryllium disease (CBD) in a cohort of workers from a nuclear weapons research and development facility.

Methods

We evaluated 50 workers with BeS with medical and occupational histories, physical examination, chest imaging with high-resolution computed tomography (N = 49), and pulmonary function testing. Forty of these workers also underwent bronchoscopy for bronchoalveolar lavage and transbronchial biopsies.

Results

The mean duration of employment at the facility was 18 years and the mean latency (from first possible exposure) to time of evaluation was 32 years. Five of the workers had CBD at the time of evaluation (based on histology or high-resolution computed tomography); three others h

SUBMITTER: Arjomandi M 

PROVIDER: S-EPMC3313491 | biostudies-literature | 2010 Jun

REPOSITORIES: biostudies-literature