Reliable identification at the species level of Brucella isolates with MALDI-TOF-MS.

ABSTRACT:

Background

The genus Brucella contains highly infectious species that are classified as biological threat agents. The timely detection and identification of the microorganism involved is essential for an effective response not only to biological warfare attacks but also to natural outbreaks. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) is a rapid method for the analysis of biological samples. The advantages of this method, compared to conventional techniques, are rapidity, cost-effectiveness, accuracy and suitability for the high-throughput identification of bacteria. Discrepancies between taxonomy and genetic relatedness on the species and biovar level complicate the development of detection and identification assays.

Results

I

SUBMITTER: Lista F 

PROVIDER: S-EPMC3314589 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature