Adiponectin and carotid intima-media thickness in the northern Manhattan study.

ABSTRACT:

Background and purpose

Adiponectin is an insulin-sensitizing plasma protein expressed in adipose tissue and suggested to play a role in atherosclerosis and cardiovascular disease. Data are lacking on the relationship between adiponectin and carotid intima-media thickness (IMT) in ethnically heterogeneous populations. We examined the relationship between adiponectin and IMT, a marker of atherosclerosis, in a multiethnic cohort study of stroke risk factors.

Methods

Participants were from the Northern Manhattan Study (N=1522, mean age 66±9 years, 60% female, 20% black, 18% white, 60% Hispanic). Adiponectin was measured from baseline plasma samples and IMT was assessed by high-resolution B-mode carotid ultrasound. Regression models were used to examine the association between ad

SUBMITTER: Gardener H 

PROVIDER: S-EPMC3314722 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature