A computerized treatment algorithm trial to optimize mineral metabolism in ESRD.

ABSTRACT:

Background and objectives

Achievement of mineral targets in patients receiving dialysis remains challenging. This study sought to evaluate outcomes for phosphorus, calcium, and parathyroid hormone when a dialysis population was switched from a predominantly active vitamin D analogue treatment regimen to a computerized algorithm incorporating both cinacalcet and active vitamin D as potential first-line therapies.

Design, setting, participants, & measurements

This longitudinal prospective trial enrolled 92 patients undergoing maintenance hemodialysis. Baseline measures (the average of the 3 months before computerized algorithm implementation) were compared with the proportion of patients achieving the prespecified targets at 6 and 12 months.

Results

After 6 months there

SUBMITTER: Spiegel DM 

PROVIDER: S-EPMC3315337 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature