Reactive strategies for containing developing outbreaks of pandemic influenza.

ABSTRACT:

Background

In 2009 and the early part of 2010, the northern hemisphere had to cope with the first waves of the new influenza A (H1N1) pandemic. Despite high-profile vaccination campaigns in many countries, delays in administration of vaccination programs were common, and high vaccination coverage levels were not achieved. This experience suggests the need to explore the epidemiological and economic effectiveness of additional, reactive strategies for combating pandemic influenza.

Methods

We use a stochastic model of pandemic influenza to investigate realistic strategies that can be used in reaction to developing outbreaks. The model is calibrated to documented illness attack rates and basic reproductive number (R0) estimates, and constructed to represent a typical mid-sized

SUBMITTER: Andradottir S 

PROVIDER: S-EPMC3317583 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature