Specificity of transcranial sonography in parkinson spectrum disorders in comparison to degenerative cognitive syndromes.

ABSTRACT:

Background

Hyperechogenicity of the substantia nigra (SN+), detected by transcranial sonography (TCS), was reported as a characteristic finding in Parkinson's disease (PD), with high diagnostic accuracy values, when compared mainly to healthy controls or essential tremor (ET) group. However, some data is accumulating that the SN + could be detected in other neurodegenerative and even in non-neurodegenerative disorders too. Our aim was to estimate the diagnostic accuracy of TCS, mainly focusing on the specificity point, when applied to a range of the parkinsonian disorders, and comparing to the degenerative cognitive syndromes.

Methods

A prospective study was carried out at the Hospital of Lithuanian University of Health Sciences from January until September 2011. Initially,

SUBMITTER: Lauckaite K 

PROVIDER: S-EPMC3317847 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature