Ontology highlight
ABSTRACT:
SUBMITTER: Guruharsha KG
PROVIDER: S-EPMC3319048 | biostudies-literature | 2011 Oct
REPOSITORIES: biostudies-literature
Cell 20111001 3
Determining the composition of protein complexes is an essential step toward understanding the cell as an integrated system. Using coaffinity purification coupled to mass spectrometry analysis, we examined protein associations involving nearly 5,000 individual, FLAG-HA epitope-tagged Drosophila proteins. Stringent analysis of these data, based on a statistical framework designed to define individual protein-protein interactions, led to the generation of a Drosophila protein interaction map (DPiM ...[more]