Study factors influencing ventricular enlargement in schizophrenia: a 20 year follow-up meta-analysis.

ABSTRACT: A meta-analysis was performed on studies employing the ventricular-brain ratio to compare schizophrenic subjects to that of normal controls. This was a follow-up to a similar meta-analysis published in 1992 in which study-, in addition to clinical-, factors were found to contribute significantly to the reported difference between patients with schizophrenia and controls. Seventy-two (N=72) total studies were identified from the peer reviewed literature, 39 from the original meta-analysis, and 33 additional studies published since which met strict criteria for inclusion and analysis - thus representing ~30 years of schizophrenia ventricular enlargement research. Sample characteristics from schizophrenics and controls were coded for use as predictor variables against within sample VBR values

SUBMITTER: Sayo A 

PROVIDER: S-EPMC3319053 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature