Structure, assembly and reading of centromeric chromatin.

ABSTRACT: Centromeres are epigenetically defined chromatin domains marked by the presence of the histone H3 variant CENP-A. Here we review recent structural and biochemical work on CENP-A, and advances in understanding the mechanisms that propagate and read centromeric chromatin domains.

SUBMITTER: Maddox PS 

PROVIDER: S-EPMC3319190 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature