Primary hyperparathyroidism and celiac disease: a population-based cohort study.

ABSTRACT:

Context

Celiac disease (CD) has been linked to several endocrine disorders, including type 1 diabetes and thyroid disorders, but little is known regarding its association to primary hyperparathyroidism (PHPT).

Objective

The aim of the study was to examine the risk of PHPT in patients with CD.

Design and setting

We conducted a two-group exposure-matched nonconcurrent cohort study in Sweden. A Cox regression model estimated hazard ratios (HR) for PHPT.

Participants

We identified 17,121 adult patients with CD who were diagnosed through biopsy reports (Marsh 3, villous atrophy) from all 28 pathology departments in Sweden. Biopsies were performed in 1969-2008, and biopsy report data were collected in 2006-2008. Statistics Sweden then identified 85,166 reference indi

SUBMITTER: Ludvigsson JF 

PROVIDER: S-EPMC3319223 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature