Molecular Modelling of Oligomeric States of DmOR83b, an Olfactory Receptor in D. Melanogaster.

ABSTRACT: After the discovery of the complete repertoire of D. melanogaster Olfactory Receptors (ORs), candidate ORs have been identified from at least 12 insect species from four orders (Coleoptera, Lepidoptera, Diptera, and Hymenoptera), including species of economic or medical importance. Although all ORs share the same G-protein coupled receptor structure with seven transmembrane domains, they share poor sequence identity within and between species, and have been identified mainly through genomic data analyses. To date, D. melanogaster remains the only insect species where ORs have been extensively studied, from expression pattern establishment to functional investigations. These studies have confirmed several observations made in vertebrates: one OR type is selectively expressed in a subtype of

SUBMITTER: Harini K 

PROVIDER: S-EPMC3320116 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature