Body weight impact on puberty: effects of high-calorie diet on puberty onset in female rhesus monkeys.

ABSTRACT: Secular trends toward a declining age at puberty onset with correlated changes in body weight have been reported in economically advanced countries. This has been attributed to excess calorie intake along with reduced physical activity in children. However, because the timing of puberty in humans is also influenced by other factors, such as genetic traits, living conditions, geographical location, and environmental chemicals, it is difficult to distinguish the effect of diet and body size from other factors in a human population. Here we report that feeding juvenile female rhesus monkeys born and raised at the Wisconsin National Primate Research Center with a high-calorie diet results in acceleration of body growth and precocious menarche. The monkeys fed a high-calorie diet also had an el

SUBMITTER: Terasawa E 

PROVIDER: S-EPMC3320255 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature