Ontology highlight
ABSTRACT:
SUBMITTER: Wang K
PROVIDER: S-EPMC3320515 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Nature 20101201 7329
Neuroblastoma is a childhood cancer of the sympathetic nervous system that accounts for approximately 10% of all paediatric oncology deaths. To identify genetic risk factors for neuroblastoma, we performed a genome-wide association study (GWAS) on 2,251 patients and 6,097 control subjects of European ancestry from four case series. Here we report a significant association within LIM domain only 1 (LMO1) at 11p15.4 (rs110419, combined P = 5.2 × 10(-16), odds ratio of risk allele = 1.34 (95% confi ...[more]