Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths.

ABSTRACT:

Background

In the National Polyp Study (NPS), colorectal cancer was prevented by colonoscopic removal of adenomatous polyps. We evaluated the long-term effect of colonoscopic polypectomy in a study on mortality from colorectal cancer.

Methods

We included in this analysis all patients prospectively referred for initial colonoscopy (between 1980 and 1990) at NPS clinical centers who had polyps (adenomas and nonadenomas). The National Death Index was used to identify deaths and to determine the cause of death; follow-up time was as long as 23 years. Mortality from colorectal cancer among patients with adenomas removed was compared with the expected incidence-based mortality from colorectal cancer in the general population, as estimated from the Surveillance Epidemiology and End

SUBMITTER: Zauber AG 

PROVIDER: S-EPMC3322371 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature