Immunofluorescence assay for serologic diagnosis of SARS.

ABSTRACT: We evaluated an indirect immunofluorescence assay based on virus-infected cells for detecting anti-severe acute respiratory syndrome-associated coronavirus (SARS-CoV) immunoglobulin (Ig) G antibody. All confirmed SARS cases demonstrated seroconversion or fourfold rise in IgG antibody titer; no control was positive. Sensitivity and specificity of this assay were both 100%. Immunofluorescence assay can ascertain the status of SARS-CoV infection.

SUBMITTER: Chan PK 

PROVIDER: S-EPMC3322771 | biostudies-literature | 2004 Mar

REPOSITORIES: biostudies-literature