Effect of stressful life events on the onset and duration of recurrent aphthous stomatitis.

ABSTRACT:

Background

Recurrent aphthous stomatitis (RAS) is a common and painful oral mucosal disease. Possible etiologies include genetics, vitamin deficiencies, trauma, immune dysfunction, and stress. The goal of this study was to examine the relationship between the occurrence, type, and magnitude of stressful events and the onset and duration of RAS episodes.

Methods

One hundred and sixty subjects with a history of RAS completed a weekly phone survey for up to 1 year, providing data on the occurrence of RAS episodes and details of any stressful events they experienced during the previous week. During RAS episodes, subjects also completed daily paper diaries that recorded incidence and duration of the RAS episode. Stressful events were quantified using the validated Recent Life Cha

SUBMITTER: Huling LB 

PROVIDER: S-EPMC3323121 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature