Oral phenotype and scoring of vascular Ehlers-Danlos syndrome: a case-control study.

ABSTRACT:

Objective

Vascular Ehlers-Danlos syndrome (vEDS) is a rare genetic condition related to mutations in the COL3A1 gene, responsible of vascular, digestive and uterine accidents. Difficulty of clinical diagnosis has led to the design of diagnostic criteria, summarised in the Villefranche classification. The goal was to assess oral features of vEDS. Gingival recession is the only oral sign recognised as a minor diagnostic criterion. The authors aimed to check this assumption since bibliographical search related to gingival recession in vEDS proved scarce.

Design

Prospective case-control study.

Setting

Dental surgery department in a French tertiary hospital.

Participants

17 consecutive patients with genetically proven vEDS, aged 19-55 years, were compared with 46 ag

SUBMITTER: Ferre FC 

PROVIDER: S-EPMC3323826 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature