Palladium-catalyzed hydrofunctionalization of vinyl phenol derivatives with heteroaromatics.

ABSTRACT: A hydroheteroarylation reaction of vinyl phenols using an alkyl chloride as the sacrificial hydride source is reported. The method tolerates a wide range of heterocycles as the exogenous nucleophile including indoles and pyrroles. The resulting products are easily processed to biologically relevant scaffolds.

SUBMITTER: Pathak TP 

PROVIDER: S-EPMC3324091 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature