WHIDE--a web tool for visual data mining colocation patterns in multivariate bioimages.

ABSTRACT:

Motivation

Bioimaging techniques rapidly develop toward higher resolution and dimension. The increase in dimension is achieved by different techniques such as multitag fluorescence imaging, Matrix Assisted Laser Desorption / Ionization (MALDI) imaging or Raman imaging, which record for each pixel an N-dimensional intensity array, representing local abundances of molecules, residues or interaction patterns. The analysis of such multivariate bioimages (MBIs) calls for new approaches to support users in the analysis of both feature domains: space (i.e. sample morphology) and molecular colocation or interaction. In this article, we present our approach WHIDE (Web-based Hyperbolic Image Data Explorer) that combines principles from computational learning, dimension reduction and visualiz

SUBMITTER: Kolling J 

PROVIDER: S-EPMC3324520 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature