Spontaneous resting-state BOLD fluctuations reveal persistent domain-specific neural networks.

ABSTRACT: Resting-state functional connectivity MRI (rs-fcMRI) analyses have identified intrinsic neural networks supporting domain-general cognitive functions including language, attention, executive control and memory. The brain, however, also has a domain-specific organization, including regions that contribute to perceiving and knowing about others (the 'social' system) or manipulable objects designed to perform specific functions (the 'tool' system). These 'social' and 'tool' systems, however, might not constitute intrinsic neural networks per se, but rather only come online as needed to support retrieval of domain-specific information during social- or tool-related cognitive tasks. To address this issue, we functionally localized two regions in lateral temporal cortex activated when subjects p

SUBMITTER: Simmons WK 

PROVIDER: S-EPMC3324567 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature