Ontology highlight
ABSTRACT:
SUBMITTER: Hamilton BA
PROVIDER: S-EPMC3325199 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Hamilton Bruce A BA Yu Benjamin D BD Yu Benjamin D BD
PLoS genetics 20120412 4
Modifier genes are an integral part of the genetic landscape in both humans and experimental organisms, but have been less well explored in mammals than other systems. A growing number of modifier genes in mouse models of disease nonetheless illustrate the potential for novel findings, while new technical advances promise many more to come. Modifier genes in mouse models include induced mutations and spontaneous or wild-derived variations captured in inbred strains. Identification of modifiers a ...[more]