Hypertonic dextrose injections (prolotherapy) for knee osteoarthritis: results of a single-arm uncontrolled study with 1-year follow-up.

ABSTRACT:

Objective

The objective of this study was to determine whether prolotherapy, an injection-based complementary treatment for chronic musculoskeletal conditions, improves pain, stiffness, and function in adults with symptomatic knee osteoarthritis (KOA) compared to baseline status.

Design

This was a prospective, uncontrolled study with 1-year follow-up.

Setting

The study was conducted in an outpatient setting.

Participants

Adults with at least 3 months of symptomatic KOA, recruited from clinical and community settings, participated in the study.

Interventions

Participants received extra-articular injections of 15% dextrose and intra-articular prolotherapy injections of 25% dextrose at 1, 5, and 9 weeks, with as-needed treatments at weeks 13 and 17.

Outc

SUBMITTER: Rabago D 

PROVIDER: S-EPMC3326267 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature