Effect of increasing doses of saw palmetto extract on lower urinary tract symptoms: a randomized trial.

ABSTRACT:

Context

Saw palmetto fruit extracts are widely used for treating lower urinary tract symptoms attributed to benign prostatic hyperplasia (BPH); however, recent clinical trials have questioned their efficacy, at least at standard doses (320 mg/d).

Objective

To determine the effect of saw palmetto extract (Serenoa repens, from saw palmetto berries) at up to 3 times the standard dose on lower urinary tract symptoms attributed to BPH.

Design, setting, and participants

A double-blind, multicenter, placebo-controlled randomized trial at 11 North American clinical sites conducted between June 5, 2008, and October 10, 2010, of 369 men aged 45 years or older, with a peak urinary flow rate of at least 4 mL/s, an American Urological Association Symptom Index (AUASI) score of bet

SUBMITTER: Barry MJ 

PROVIDER: S-EPMC3326341 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature