Ontology highlight
ABSTRACT:
SUBMITTER: Quilichini PP
PROVIDER: S-EPMC3328133 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Neuron 20120401 1
Gamma-frequency oscillations (GFOs, >40 Hz) are a general network signature at seizure onset at all stages of development, with possible deleterious consequences in the immature brain. At early developmental stages, the simultaneous occurrence of GFOs in different brain regions suggests the existence of a long-ranging synchronizing mechanism at seizure onset. Here, we show that hippocamposeptal (HS) neurons, which are GABA long-range projection neurons, are mandatory to drive the firing of hippo ...[more]