Neural correlates of perceptual decision making before, during, and after decision commitment in monkey frontal eye field.

ABSTRACT: Perceptual decision making requires a complex set of computations to implement, evaluate, and adjust the conversion of sensory input into a categorical judgment. Little is known about how the specific underlying computations are distributed across and within different brain regions. Using a reaction-time (RT) motion direction-discrimination task, we show that a unique combination of decision-related signals is represented in monkey frontal eye field (FEF). Some responses were modulated by choice, motion strength, and RT, consistent with a temporal accumulation of sensory evidence. These responses converged to a threshold level prior to behavioral responses, reflecting decision commitment. Other responses continued to be modulated by motion strength even after decision commitment, possibly

SUBMITTER: Ding L 

PROVIDER: S-EPMC3328342 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature