Dengue deaths in Puerto Rico: lessons learned from the 2007 epidemic.

ABSTRACT:

Background

The incidence and severity of dengue in Latin America has increased substantially in recent decades and data from Puerto Rico suggests an increase in severe cases. Successful clinical management of severe dengue requires early recognition and supportive care.

Methods

Fatal cases were identified among suspected dengue cases reported to two disease surveillance systems and from death certificates. To be included, fatal cases had to have specimen submitted for dengue diagnostic testing including nucleic acid amplification for dengue virus (DENV) in serum or tissue, immunohistochemical testing of tissue, and immunoassay detection of anti-DENV IgM from serum. Medical records from laboratory-positive dengue fatal case-patients were reviewed to identify possible determin

SUBMITTER: Tomashek KM 

PROVIDER: S-EPMC3328431 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature