HD-RNAS: An Automated Hierarchical Database of RNA Structures.

ABSTRACT: One of the important goals of most biological investigations is to classify and organize the experimental findings so that they are readily useful for deriving generalized rules. Although there is a huge amount of information on RNA structures in PDB, there are redundant files, ambiguous synthetic sequences etc. Moreover, a systematic hierarchical organization, reflecting RNA classification, is missing in PDB. In this investigation, we have classified all the available RNA structures from PDB through a programmatic approach. Hence, it would be now a simple assignment to regularly update the classification as and when new structures are released. The classification can further determine (i) a non-redundant set of RNA structures and (ii) if available, a set of structures of identical sequenc

SUBMITTER: Ray SS 

PROVIDER: S-EPMC3329738 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature