IronXS: high-school screening for hereditary haemochromatosis is acceptable and feasible.

ABSTRACT: As the results of the Human Genome Project are realised, screening for genetic mutations that predispose to preventable disease is becoming increasingly possible. How and where such screening should best be offered are critical, unanswered questions. This study aimed to assess the acceptability and feasibility of genetic screening for preventable disease, using the model of hereditary haemochromatosis, in high-school students. Screening was offered for the HFE C282Y substitution to 17,638 students. Questionnaires were administered at the time of screening (Q1) and approximately 1 month after results were communicated (Q2). Outcomes assessed were uptake of screening, change in scores of validated anxiety, affect and health perception scales from Q1 to Q2, knowledge and iron indices in C282Y

SUBMITTER: Delatycki MB 

PROVIDER: S-EPMC3330225 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature